View source for 9hqn


==Cryo-EM structure of bovine TMEM206==
<StructureSection load='9hqn' size='340' side='right'caption='[[9hqn]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9hqn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HQN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.86&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hqn OCA], [https://pdbe.org/9hqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hqn RCSB], [https://www.ebi.ac.uk/pdbsum/9hqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hqn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PACC1_BOVIN PACC1_BOVIN] Chloride channel gated by pH that facilitates the entry of chloride ions into cells upon exposure to extracellular acidic pH. Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling.[UniProtKB:Q9H813]
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Brunner JD]]
[[Category: De Gieter S]]
[[Category: Schenck S]]