View source for 9hua


==Glycosyltransferase C from the Limosilactobacillus reuteri accessory secretion system. Complex with UDP.==
<StructureSection load='9hua' size='340' side='right'caption='[[9hua]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9hua]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Limosilactobacillus_reuteri Limosilactobacillus reuteri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HUA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hua OCA], [https://pdbe.org/9hua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hua RCSB], [https://www.ebi.ac.uk/pdbsum/9hua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hua ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GTF3_LIMR1 GTF3_LIMR1] Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the second step in glycosylation by transferring glucose from UDP-glucose to the terminal GlcNAc moiety of the 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-seryl-[protein] resulting from the first glycosylation step.<ref>PMID:30371779</ref>   Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall protein(s) encoded upstream in the same operon.<ref>PMID:30371779</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Limosilactobacillus reuteri]]
[[Category: Asworth GJ]]
[[Category: Dong CJ]]
[[Category: Griffiths R]]
[[Category: Hemmings AM]]
[[Category: Juge N]]