View source for 9hyk


==Crystal structure of Trypanosoma brucei trypanothione reductase (TbTR) bound to PROTAC-1==
<StructureSection load='9hyk' size='340' side='right'caption='[[9hyk]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9hyk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HYK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1IYC:2-[2-[2-[[2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]-1,3-bis(oxidanylidene)isoindol-4-yl]amino]ethoxy]ethoxy]-~{N}-[3-[(4~{S})-6-chloranyl-2-methyl-4-phenyl-4~{H}-quinazolin-3-yl]propyl]ethanamide'>A1IYC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hyk OCA], [https://pdbe.org/9hyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hyk RCSB], [https://www.ebi.ac.uk/pdbsum/9hyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hyk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q389T8_TRYB2 Q389T8_TRYB2] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Exertier C]]
[[Category: Fiorillo A]]
[[Category: Ilari C]]