View source for 9ibi


==Solution NMR study of the titin I-band IgI domain I82 reveals conformational dynamics==
<StructureSection load='9ibi' size='340' side='right'caption='[[9ibi]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ibi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IBI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR,  models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ibi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ibi OCA], [https://pdbe.org/9ibi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ibi RCSB], [https://www.ebi.ac.uk/pdbsum/9ibi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ibi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TITIN_MOUSE TITIN_MOUSE] Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.[UniProtKB:Q8WZ42]<ref>PMID:16702235</ref> <ref>PMID:17261657</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Gage M]]
[[Category: Pfuhl M]]