View source for 9ipu


==cryo-EM structure of the RNF168(1-193)/UbcH5c-Ub ubiquitylation module bound to H1.0-K63-Ub3 modified chromatosome==
<StructureSection load='9ipu' size='340' side='right'caption='[[9ipu]], [[Resolution|resolution]] 4.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ipu]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IPU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ipu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ipu OCA], [https://pdbe.org/9ipu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ipu RCSB], [https://www.ebi.ac.uk/pdbsum/9ipu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ipu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/H10_HUMAN H10_HUMAN] Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ai HS]]
[[Category: Deng ZH]]
[[Category: Liu L]]