View source for 9iwv


==Crystal structure of Lsd18 after incubation with the substrate==
<StructureSection load='9iwv' size='340' side='right'caption='[[9iwv]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9iwv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lasalocidi Streptomyces lasalocidi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IWV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ELY:N~6~,N~6~-DIETHYL-L-LYSINE'>ELY</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9iwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9iwv OCA], [https://pdbe.org/9iwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9iwv RCSB], [https://www.ebi.ac.uk/pdbsum/9iwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9iwv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LSD18_STRLS LSD18_STRLS] May catalyze the stereoselective double epoxidation reaction leading to bisepoxyprelasalocid A, a bisepoxide intermediate in the biosynthesis of the polyether antibiotic lasalocid A.<ref>PMID:19025863</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces lasalocidi]]
[[Category: Chen X]]
[[Category: Kim CY]]
[[Category: Wang Q]]