View source for 9ixx


==Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4==
<StructureSection load='9ixx' size='340' side='right'caption='[[9ixx]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ixx]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IXX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LTD:(5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-AZANYL-3-(2-HYDROXY-2-OXOETHYLAMINO)-3-OXIDANYLIDENE-PROPYL]SULFANYL-5-OXIDANYL-ICOSA-7,9,11,14-TETRAENOIC+ACID'>LTD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ixx OCA], [https://pdbe.org/9ixx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ixx RCSB], [https://www.ebi.ac.uk/pdbsum/9ixx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ixx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Jiang M]]
[[Category: Xu Y]]
[[Category: Yin W]]