View source for 9izd


==Cryo-EM structure of human HCAR1-Gi complex with CHBA==
<StructureSection load='9izd' size='340' side='right'caption='[[9izd]], [[Resolution|resolution]] 3.16&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9izd]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IZD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.16&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1D71:3-chloranyl-5-oxidanyl-benzoic+acid'>A1D71</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9izd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9izd OCA], [https://pdbe.org/9izd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9izd RCSB], [https://www.ebi.ac.uk/pdbsum/9izd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9izd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HCAR1_HUMAN HCAR1_HUMAN] Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.<ref>PMID:19047060</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Fang Y]]
[[Category: Xin P]]