View source for 9jal


==Cryo-EM structure of MPXV core protease in complex with compound A1==
<StructureSection load='9jal' size='340' side='right'caption='[[9jal]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9jal]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JAL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.03&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1ECM:(2~{S})-3,3-dimethyl-2-(methylsulfonylamino)butanoic+acid'>A1ECM</scene>, <scene name='pdbligand=DI8:(3S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC+ACID'>DI8</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jal OCA], [https://pdbe.org/9jal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jal RCSB], [https://www.ebi.ac.uk/pdbsum/9jal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jal ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5IXV7_MONPV Q5IXV7_MONPV] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Monkeypox virus]]
[[Category: Synthetic construct]]
[[Category: Gao Y]]
[[Category: Lan W]]
[[Category: Wang W]]
[[Category: Xie X]]
[[Category: Yang H]]