View source for 9jb3


==Crystal structure of DH domain of human FGD6==
<StructureSection load='9jb3' size='340' side='right'caption='[[9jb3]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9jb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JB3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jb3 OCA], [https://pdbe.org/9jb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jb3 RCSB], [https://www.ebi.ac.uk/pdbsum/9jb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jb3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FGD6_HUMAN FGD6_HUMAN] May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity).
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chuan JL]]
[[Category: Liu ZC]]
[[Category: Wang GG]]