View source for 9jcj


==Cryo-EM structure of asymmetric pannexin 3 heptamer in GDN class 1==
<StructureSection load='9jcj' size='340' side='right'caption='[[9jcj]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9jcj]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JCJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jcj OCA], [https://pdbe.org/9jcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jcj RCSB], [https://www.ebi.ac.uk/pdbsum/9jcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jcj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PANX3_HUMAN PANX3_HUMAN] Regulator of osteoblast differentiation by functionning as a Ca(2+) channel in the endoplasmic reticulum which regulates calmodulin (CaM) pathways. Allows ATP release into the extracellular space and activation or purinergic receptors.[UniProtKB:Q8CEG0]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Wang D]]
[[Category: Zhang H]]
[[Category: Zhang HW]]