View source for 9jdn


==Crystal structure of alanyl-tRNA synthetase L219M mutant in complex with ATP and L-alanine==
<StructureSection load='9jdn' size='340' side='right'caption='[[9jdn]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9jdn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylomonas_sp._DH-1 Methylomonas sp. DH-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JDN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1800666&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jdn OCA], [https://pdbe.org/9jdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jdn RCSB], [https://www.ebi.ac.uk/pdbsum/9jdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jdn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A172UEB3_METSD A0A172UEB3_METSD] Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.[HAMAP-Rule:MF_00036]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methylomonas sp. DH-1]]
[[Category: Cha SS]]
[[Category: Son SY]]