View source for 9kng


==Crystal structure of human ERRg LBD in complex with 4034496==
<StructureSection load='9kng' size='340' side='right'caption='[[9kng]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9kng]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KNG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EGD:6-methyl-1,3-benzothiazole-2,4-diamine'>A1EGD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kng OCA], [https://pdbe.org/9kng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kng RCSB], [https://www.ebi.ac.uk/pdbsum/9kng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kng ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Liu J]]
[[Category: Wang N]]
[[Category: Xu T]]