View source for 9knw


==Cryo-EM structure of apo human mitochondrial pyruvate carrier in the IMS-open conformation at pH 6.8==
<StructureSection load='9knw' size='340' side='right'caption='[[9knw]], [[Resolution|resolution]] 3.41&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9knw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KNW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.41&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDL:CARDIOLIPIN'>CDL</scene>, <scene name='pdbligand=PC8:1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC8</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9knw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9knw OCA], [https://pdbe.org/9knw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9knw RCSB], [https://www.ebi.ac.uk/pdbsum/9knw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9knw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MPC2_HUMAN MPC2_HUMAN] Mediates the uptake of pyruvate into mitochondria.<ref>PMID:22628558</ref> <ref>PMID:26253029</ref> <ref>PMID:27317664</ref> <ref>PMID:29472561</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Liang JM]]
[[Category: Ma D]]
[[Category: Shi JH]]