View source for 9kp8


==Crystal structure of FAD-dependent oxidase CpaO==
<StructureSection load='9kp8' size='340' side='right'caption='[[9kp8]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9kp8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_oryzae Aspergillus oryzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KP8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.179&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kp8 OCA], [https://pdbe.org/9kp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kp8 RCSB], [https://www.ebi.ac.uk/pdbsum/9kp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kp8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0AA49QBA5_ASPNG A0AA49QBA5_ASPNG] Hydrolyzes malto-oligosaccharides, but has a low activity toward soluble starch.[ARBA:ARBA00056204][https://www.uniprot.org/uniprot/CPAO_ASPOR CPAO_ASPOR] Beta-cyclopiazonate dehydrogenase involved in the synthesis of the fungal neurotoxin alpha-cyclopiazonic acid (CPA). CpaO carries out the dehydrogenation of beta-CPA to yield an unstable enimine product, which is captured by intramolecular cyclization to create the pentacyclic fused scaffold of alpha-cyclopiazonate.<ref>PMID:21608094</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Aspergillus oryzae]]
[[Category: Large Structures]]
[[Category: Chang CY]]
[[Category: Cheng T]]
[[Category: Hsiao PY]]
[[Category: Kuo YM]]
[[Category: Liang CH]]
[[Category: Lin YC]]
[[Category: Wang N]]