View source for 9ktq


==Crystal structure of the pathogen-secreted apoplastic GH12 xyloglucan-specific endoglucanase XEG1==
<StructureSection load='9ktq' size='340' side='right'caption='[[9ktq]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ktq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Phytophthora_sojae_strain_P6497 Phytophthora sojae strain P6497]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KTQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KTQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ktq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ktq OCA], [https://pdbe.org/9ktq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ktq RCSB], [https://www.ebi.ac.uk/pdbsum/9ktq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ktq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/XEG1_PHYSP XEG1_PHYSP] Glycoside hydrolase that exhibits xyloglucanase activity (PubMed:26163574). Acts as an important virulence factor during P.sojae infection but also acts as a pathogen-associated molecular pattern (PAMP) in soybean and solanaceous species, where it can trigger defense responses including cell death. XEG1-induced cell death can be suppressed by P.sojae RxLR effectors. The PAMP activity is independent of its xyloglucanase activity (PubMed:26163574). XEG1 induces plant defense responses in a RLP kinase Serk3/Bak1-dependent manner in Nicotiana benthamiana. Moreover, the perception of XEG1 occurs independently of the perception of ethylene-inducing xylanase Eix2 in Tomato (PubMed:26163574). With truncated paralog XLP1, is required to elevate apoplastic sugar during P.sojae infection (PubMed:28082413).<ref>PMID:26163574</ref> <ref>PMID:28082413</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Phytophthora sojae strain P6497]]
[[Category: He XY]]
[[Category: Jiang HB]]
[[Category: Liu L]]
[[Category: Ma ZC]]
[[Category: Shi XC]]
[[Category: Wang Y]]
[[Category: Wang YC]]
[[Category: Wang ZK]]
[[Category: Wang ZY]]
[[Category: Xia YQ]]
[[Category: Xiao JH]]
[[Category: Yang Q]]
[[Category: Yang YH]]
[[Category: Ye WW]]
[[Category: Zhang Q]]
[[Category: Zhang SC]]
[[Category: Zhang ZC]]