View source for 9l2n


==Crystal structure of Cytochalasin D bound to a filamentous conformation actin==
<StructureSection load='9l2n' size='340' side='right'caption='[[9l2n]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9l2n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Physarum_polycephalum Physarum polycephalum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L2N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L2N FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CY9:(3S,3AR,4S,6S,6AR,7E,10S,12R,13E,15R,15AR)-3-BENZYL-6,12-DIHYDROXY-4,10,12-TRIMETHYL-5-METHYLIDENE-1,11-DIOXO-2,3,3A,4,5,6,6A,9,10,11,12,15-DODECAHYDRO-1H-CYCLOUNDECA[D]ISOINDOL-15-YL+ACETATE'>CY9</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l2n OCA], [https://pdbe.org/9l2n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l2n RCSB], [https://www.ebi.ac.uk/pdbsum/9l2n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l2n ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACTS_CHICK ACTS_CHICK] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Physarum polycephalum]]
[[Category: Fujiwara I]]
[[Category: Maeda Y]]
[[Category: Takeda S]]