View source for 9l38


==Structure of ENBT1 in the apo state==
<StructureSection load='9l38' size='340' side='right'caption='[[9l38]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9l38]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L38 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l38 OCA], [https://pdbe.org/9l38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l38 RCSB], [https://www.ebi.ac.uk/pdbsum/9l38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l38 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/S43A3_HUMAN S43A3_HUMAN] Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine (PubMed:26455426, PubMed:32339528). May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity).[UniProtKB:A2AVZ9]<ref>PMID:26455426</ref> <ref>PMID:32339528</ref>   Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine (PubMed:30910793). Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane (PubMed:30910793).<ref>PMID:30910793</ref>   Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine (PubMed:30910793). Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane (PubMed:30910793).<ref>PMID:30910793</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ding D]]
[[Category: Lu YS]]
[[Category: Yin YX]]