View source for 9lkr


==Crystal Structure of the bromodomain of human BRD9 in complex with the inhibitor Y22076==
<StructureSection load='9lkr' size='340' side='right'caption='[[9lkr]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9lkr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LKR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.68&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EKN:1-[1-[4-(imidazol-1-ylmethyl)-3,5-dimethoxy-phenyl]indolizin-3-yl]ethanone'>A1EKN</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lkr OCA], [https://pdbe.org/9lkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lkr RCSB], [https://www.ebi.ac.uk/pdbsum/9lkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lkr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chen Z]]
[[Category: Wu X]]
[[Category: Xu H]]
[[Category: Xu Y]]
[[Category: Zhang C]]
[[Category: Zhang Y]]