View source for 9lnf


==Crystal structure of SpoIVB_101-426-S378A==
<StructureSection load='9lnf' size='340' side='right'caption='[[9lnf]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9lnf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LNF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lnf OCA], [https://pdbe.org/9lnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lnf RCSB], [https://www.ebi.ac.uk/pdbsum/9lnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lnf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SP4B_BACSU SP4B_BACSU] Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter.<ref>PMID:10931284</ref> <ref>PMID:11741860</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Large Structures]]
[[Category: Huang MD]]
[[Category: Jiang LG]]
[[Category: Zhu J]]