View source for 9lot


==Crystal structure of Escherichia coli trptophanyl-tRNA synthetase in complex with N-piperidine ibrutinib==
<StructureSection load='9lot' size='340' side='right'caption='[[9lot]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9lot]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LOT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EKY:3-(4-phenoxyphenyl)-1-piperidin-4-yl-pyrazolo[3,4-d]pyrimidin-4-amine'>A1EKY</scene>, <scene name='pdbligand=CLW:CHLORZOXAZONE'>CLW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYM:TRYPTOPHANYL-5AMP'>TYM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lot OCA], [https://pdbe.org/9lot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lot RCSB], [https://www.ebi.ac.uk/pdbsum/9lot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lot ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/E2QFN4_ECOLX E2QFN4_ECOLX] Catalyzes the attachment of tryptophan to tRNA(Trp).[HAMAP-Rule:MF_00140]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Chen B]]
[[Category: Peng X]]
[[Category: Xia K]]
[[Category: Zhou H]]