View source for 9lum


==Cryo-EM structure of Arabidopsis thaliana RGA in complex with GID1A==
<StructureSection load='9lum' size='340' side='right'caption='[[9lum]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9lum]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LUM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.66&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GA3:GIBBERELLIN+A3'>GA3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lum OCA], [https://pdbe.org/9lum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lum RCSB], [https://www.ebi.ac.uk/pdbsum/9lum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lum ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RGA_ARATH RGA_ARATH] Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression in seeds. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Compared to other DELLA proteins, it is the most sensitive to GA application. No effect of the BOI proteins on its stability. Its activity is probably regulated by other phytohormones such as auxin and ethylene, attenuation of auxin transport delaying its GA-induced degradation. Involved in the regulation of seed dormancy and germination, including glucose-induced delay of seed germination (PubMed:24989044).<ref>PMID:11606551</ref> <ref>PMID:11606552</ref> <ref>PMID:12610625</ref> <ref>PMID:14615596</ref> <ref>PMID:14973286</ref> <ref>PMID:15128937</ref> <ref>PMID:16034591</ref> <ref>PMID:17933900</ref> <ref>PMID:20093430</ref> <ref>PMID:24989044</ref> <ref>PMID:9490740</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Islam S]]
[[Category: Kim DY]]
[[Category: Kwon E]]
[[Category: Park K]]