View source for 9lx0


==DOCK5/ELMO1 complex with RhoG and Rac1 on lipid membrane==
<StructureSection load='9lx0' size='340' side='right'caption='[[9lx0]], [[Resolution|resolution]] 6.98&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9lx0]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LX0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.98&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lx0 OCA], [https://pdbe.org/9lx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lx0 RCSB], [https://www.ebi.ac.uk/pdbsum/9lx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lx0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ELMO1_HUMAN ELMO1_HUMAN] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.<ref>PMID:11595183</ref> <ref>PMID:12134158</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Katsura K]]
[[Category: Kukimoto-Niino M]]
[[Category: Shinoda T]]
[[Category: Shirouzu M]]