View source for 9lxn


==Human RNA Polymerase III de novo transcribing complex 5 (TC5)(without 3'dATP)==
<StructureSection load='9lxn' size='340' side='right'caption='[[9lxn]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9lxn]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LXN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lxn OCA], [https://pdbe.org/9lxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lxn RCSB], [https://www.ebi.ac.uk/pdbsum/9lxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lxn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SNPC1_HUMAN SNPC1_HUMAN] Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.<ref>PMID:12621023</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chen X]]
[[Category: Jin Q]]
[[Category: Ren Y]]
[[Category: Wang Q]]
[[Category: Xu Y]]