View source for 9mmp


==Cryo-EM structure of CRAF/MEK1/14-3-3 complex (autoinhibited conformation)==
<StructureSection load='9mmp' size='340' side='right'caption='[[9mmp]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9mmp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Spodoptera_exigua Spodoptera exigua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MMP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=LCJ:5-[(2-fluoranyl-4-iodanyl-phenyl)amino]-~{N}-(2-hydroxyethyloxy)imidazo[1,5-a]pyridine-6-carboxamide'>LCJ</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mmp OCA], [https://pdbe.org/9mmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mmp RCSB], [https://www.ebi.ac.uk/pdbsum/9mmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mmp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/V9P4T4_SPOEX V9P4T4_SPOEX] 
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Spodoptera exigua]]
[[Category: Eck MJ]]
[[Category: Jang DM]]
[[Category: Jeon H]]