View source for 9ndq


==The rigid portion of Cryo-EM structure of Herpesvirus Helicase-Primase complex prepared with forked DNA and ATP-gamma-S==
<StructureSection load='9ndq' size='340' side='right'caption='[[9ndq]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ndq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Herpesviridae Herpesviridae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NDQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NDQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ndq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ndq OCA], [https://pdbe.org/9ndq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ndq RCSB], [https://www.ebi.ac.uk/pdbsum/9ndq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ndq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRIM_HHV11 PRIM_HHV11] Essential component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.[HAMAP-Rule:MF_04011]<ref>PMID:7775476</ref> <ref>PMID:8189507</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Herpesviridae]]
[[Category: Large Structures]]
[[Category: Yao Q]]
[[Category: Yu X]]