View source for 9nor


==Human sweet taste receptor composed of TAS1R2 and TAS1R3 GPCRs from the combined datasets==
<StructureSection load='9nor' size='340' side='right'caption='[[9nor]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9nor]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NOR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9nor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9nor OCA], [https://pdbe.org/9nor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9nor RCSB], [https://www.ebi.ac.uk/pdbsum/9nor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9nor ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TS1R3_HUMAN TS1R3_HUMAN] Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.<ref>PMID:11917125</ref> <ref>PMID:12892531</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chang AN]]
[[Category: Fitzpatrick AWP]]
[[Category: Juen Z]]
[[Category: Lu Z]]
[[Category: Wang B]]
[[Category: Yu R]]
[[Category: Zuker CS]]