View source for 9nos


==Human sweet taste receptor (TAS1R2 + TAS1R3) from the PEG400 dataset==
<StructureSection load='9nos' size='340' side='right'caption='[[9nos]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9nos]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NOS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9nos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9nos OCA], [https://pdbe.org/9nos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9nos RCSB], [https://www.ebi.ac.uk/pdbsum/9nos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9nos ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TS1R3_HUMAN TS1R3_HUMAN] Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.<ref>PMID:11917125</ref> <ref>PMID:12892531</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chang AN]]
[[Category: Fitzpatrick AWP]]
[[Category: Juen Z]]
[[Category: Lu Z]]
[[Category: Wang B]]
[[Category: Yu R]]
[[Category: Zuker CS]]