View source for 9nyr


==Cryo-EM structure of CDK2/CyclinE1 in complex with CRBN/DDB1 and Cpd 24==
<StructureSection load='9nyr' size='340' side='right'caption='[[9nyr]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9nyr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NYR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1B7G:N-{(1R,4S)-4-[(4-{3-chloro-4-[(3R)-2,6-dioxo-1,2,3,6-tetrahydropyridin-3-yl]phenyl}piperazin-1-yl)methyl]cyclohexyl}-4-({4-[(3S)-3-hydroxy-3-methylpiperidin-1-yl]-5-(trifluoromethyl)pyrimidin-2-yl}amino)-3-methylbenzene-1-sulfonamide'>A1B7G</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9nyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9nyr OCA], [https://pdbe.org/9nyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9nyr RCSB], [https://www.ebi.ac.uk/pdbsum/9nyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9nyr ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Aversa R]]
[[Category: Breitkopf SB]]
[[Category: Chen D]]
[[Category: Collier P]]
[[Category: Enerson B]]
[[Category: Ford M]]
[[Category: Growney JD]]
[[Category: Howarth L]]
[[Category: Kwiatkowski NP]]
[[Category: Li K]]
[[Category: Liang T]]
[[Category: Paul A]]
[[Category: Sathappa M]]
[[Category: Sawant R]]
[[Category: Sharma K]]
[[Category: Su L]]
[[Category: Weiss M]]
[[Category: Williams J]]
[[Category: Yang A]]
[[Category: Zheng X]]