View source for 9oq1


==Structure of the sweet receptor bound to sucralose in the loose state, extracellular domain==
<StructureSection load='9oq1' size='340' side='right'caption='[[9oq1]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9oq1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OQ1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.98&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PRD_900090:sucralose'>PRD_900090</scene>, <scene name='pdbligand=RRJ:(2~{S},3~{R},4~{R},5~{R},6~{R})-5-chloranyl-6-(hydroxymethyl)oxane-2,3,4-triol'>RRJ</scene>, <scene name='pdbligand=RRY:1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose'>RRY</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9oq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9oq1 OCA], [https://pdbe.org/9oq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9oq1 RCSB], [https://www.ebi.ac.uk/pdbsum/9oq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9oq1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TS1R2_HUMAN TS1R2_HUMAN] Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Chen X]]
[[Category: Dai Y]]
[[Category: Lee CH]]
[[Category: Wang H]]