View source for 9ptm


==Antibody fragment from mAb824 bound to the adhesin protein FimH.==
<StructureSection load='9ptm' size='340' side='right'caption='[[9ptm]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ptm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PTM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ptm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ptm OCA], [https://pdbe.org/9ptm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ptm RCSB], [https://www.ebi.ac.uk/pdbsum/9ptm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ptm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Hvorecny KL]]
[[Category: Klevit RE]]
[[Category: Kollman JM]]
[[Category: Magala P]]