View source for 9ptu


==Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12==
<StructureSection load='9ptu' size='340' side='right'caption='[[9ptu]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ptu]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PTU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PTU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1CK5:L-gamma-glutamyl-S-{6-chloro-5-[(3,5-dimethylphenoxy)carbonyl]-3-fluoropyridin-2-yl}-L-cysteinylglycine'>A1CK5</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ptu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ptu OCA], [https://pdbe.org/9ptu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ptu RCSB], [https://www.ebi.ac.uk/pdbsum/9ptu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ptu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DCA11_HUMAN DCA11_HUMAN] May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.<ref>PMID:16949367</ref> <ref>PMID:16964240</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ebert BL]]
[[Category: Fischer ES]]
[[Category: Jin CY]]
[[Category: Wachter F]]
[[Category: Yoon H]]