View source for 9qjj


==Cryo-EM structure of CDK2-cyclin A bound to OTS964==
<StructureSection load='9qjj' size='340' side='right'caption='[[9qjj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9qjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QJJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NK3:9-[4-[(2~{R})-1-(dimethylamino)propan-2-yl]phenyl]-6-methyl-8-oxidanyl-5~{H}-thieno[2,3-c]quinolin-4-one'>NK3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qjj OCA], [https://pdbe.org/9qjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qjj RCSB], [https://www.ebi.ac.uk/pdbsum/9qjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qjj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CCNA2_HUMAN CCNA2_HUMAN] Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Alfieri C]]
[[Category: Cronin NB]]
[[Category: Cushing VI]]
[[Category: Greber BJ]]
[[Category: McGeoch AJS]]