View source for 9qqv


==Structure of the F13 protein of Vaccinia virus in complex with G243-1720==
<StructureSection load='9qqv' size='340' side='right'caption='[[9qqv]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9qqv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Western_Reserve Vaccinia virus Western Reserve]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QQV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QQV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1I9D:4-(azepan-1-ylcarbonyl)-~{N}-(2-chloranyl-4-methyl-phenyl)-1,2,5-trimethyl-pyrrole-3-sulfonamide'>A1I9D</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qqv OCA], [https://pdbe.org/9qqv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qqv RCSB], [https://www.ebi.ac.uk/pdbsum/9qqv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qqv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PG057_VACCW PG057_VACCW] Major envelope protein that plays a role in the biogenesis of the viral double membrane and in egress of virus from the host cell (PubMed:17475658, PubMed:27466413, PubMed:8999886). Produces the wrapped form of virus that is required for cell-to-cell spread (PubMed:27466413, PubMed:29540596). Acts as a lipase with broad specificity including phospholipase C, phospholipase A, and triacylglycerol lipase activities (PubMed:9405398).<ref>PMID:17475658</ref> <ref>PMID:27466413</ref> <ref>PMID:29540596</ref> <ref>PMID:8999886</ref> <ref>PMID:9405398</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vaccinia virus Western Reserve]]
[[Category: Guardado-Calvo P]]
[[Category: Vernuccio R]]