View source for 9qw7


==The crystal structure of the adenyly transferase domain of Candida glabrata tRNA ligase==
<StructureSection load='9qw7' size='340' side='right'caption='[[9qw7]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9qw7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QW7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qw7 OCA], [https://pdbe.org/9qw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qw7 RCSB], [https://www.ebi.ac.uk/pdbsum/9qw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qw7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q6FJW3_CANGA Q6FJW3_CANGA] One of the two proteins required for the splicing of precursor tRNA molecules containing introns. The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' half-tRNA in the presence of ATP, opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester and ligation of the two tRNA halves in an ATP-dependent reaction.[ARBA:ARBA00055002]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Giovinazzo A]]
[[Category: McEwen AG]]
[[Category: Merolle M]]
[[Category: Pellegrini M]]
[[Category: Poussin-Courmontagne P]]
[[Category: Tocchini-Valentini GD]]
[[Category: Tocchini-Valentini GP]]