View source for 9rc1


==Cryo-ET structure of N-terminally truncated membrane-bound EHD2 complex==
<StructureSection load='9rc1' size='340' side='right'caption='[[9rc1]], [[Resolution|resolution]] 10.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9rc1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RC1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rc1 OCA], [https://pdbe.org/9rc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rc1 RCSB], [https://www.ebi.ac.uk/pdbsum/9rc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rc1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EHD2_MOUSE EHD2_MOUSE] Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP.<ref>PMID:14676205</ref> <ref>PMID:18502764</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Daumke O]]
[[Category: Kudryashev M]]
[[Category: Mikirtumov V]]
[[Category: Noel J]]
[[Category: Vazquez-Sarandeses E]]