View source for 9rdm


==SUDV VP40 in complex with 3-aminosalicylic acid==
<StructureSection load='9rdm' size='340' side='right'caption='[[9rdm]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9rdm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sudan_ebolavirus Sudan ebolavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RDM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1CW:3-AMINO-2-HYDROXYBENZOIC+ACID'>1CW</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rdm OCA], [https://pdbe.org/9rdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rdm RCSB], [https://www.ebi.ac.uk/pdbsum/9rdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rdm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VP40_EBOSU VP40_EBOSU] Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. May facilitate virus budding by interacting with the nucleocapsid and the plasma membrane. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. The hexamer form seems to be involved in budding. The octamer form binds RNA, and may play a role in genome replication (By similarity).
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</StructureSection>
[[Category: Large Structures]]
[[Category: Sudan ebolavirus]]
[[Category: Becker S]]
[[Category: Diederich W]]
[[Category: Laube L]]
[[Category: Werner A-D]]