View source for 9rhk


==Solution NMR structure of the titin I-band tandem I82-I83==
<StructureSection load='9rhk' size='340' side='right'caption='[[9rhk]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9rhk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RHK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RHK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 3 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rhk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rhk OCA], [https://pdbe.org/9rhk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rhk RCSB], [https://www.ebi.ac.uk/pdbsum/9rhk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rhk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TITIN_MOUSE TITIN_MOUSE] Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.[UniProtKB:Q8WZ42]<ref>PMID:16702235</ref> <ref>PMID:17261657</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Pfuhl M]]