View source for 9rlt


==dimerised 13S-13S+Beta5 proteasome precursor complexes==
<StructureSection load='9rlt' size='340' side='right'caption='[[9rlt]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9rlt]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RLT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.09&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rlt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rlt OCA], [https://pdbe.org/9rlt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rlt RCSB], [https://www.ebi.ac.uk/pdbsum/9rlt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rlt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSA1_YEAST PSA1_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Dohmen RJ]]
[[Category: Mark E]]
[[Category: Nunes MM]]
[[Category: Ramos PC]]
[[Category: Wendler P]]