View source for 9rm1


==13S+Beta1+Beta5 proteasome precursor complex==
<StructureSection load='9rm1' size='340' side='right'caption='[[9rm1]], [[Resolution|resolution]] 4.11&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9rm1]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RM1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.11&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rm1 OCA], [https://pdbe.org/9rm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rm1 RCSB], [https://www.ebi.ac.uk/pdbsum/9rm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rm1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSA1_YEAST PSA1_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Dohmen RJ]]
[[Category: Mark E]]
[[Category: Nunes MM]]
[[Category: Ramos PC]]
[[Category: Wendler P]]