View source for 9rrt


==Crystal structure of Borrelia recurrentis variable large protein VlpA1 (VmpA1)==
<StructureSection load='9rrt' size='340' side='right'caption='[[9rrt]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9rrt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Borrelia_recurrentis_A1 Borrelia recurrentis A1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RRT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RRT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rrt OCA], [https://pdbe.org/9rrt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rrt RCSB], [https://www.ebi.ac.uk/pdbsum/9rrt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rrt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B5RS36_BORRA B5RS36_BORRA] The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.[ARBA:ARBA00003932][RuleBase:RU363105]
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</StructureSection>
[[Category: Borrelia recurrentis A1]]
[[Category: Large Structures]]
[[Category: Blazier JC]]
[[Category: Brangulis K]]
[[Category: Gaber AM]]
[[Category: Lui C]]
[[Category: Rogovskyy AS]]
[[Category: Wiener DJ]]