View source for 9sik


==Phage epsilon15 tailspike gp20 esterase domain==
<StructureSection load='9sik' size='340' side='right'caption='[[9sik]], [[Resolution|resolution]] 1.32&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9sik]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_phage_epsilon15 Salmonella phage epsilon15]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SIK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SIK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.324&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9sik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9sik OCA], [https://pdbe.org/9sik PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9sik RCSB], [https://www.ebi.ac.uk/pdbsum/9sik PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9sik ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FIBER_BPE15 FIBER_BPE15] Structural component of the short non-contractile tail (PubMed:16452981). The tail comprises six spikes that mediate primary attachment to the host cell lipopolysaccharides (LPS) and display endorhamnosidase enzymatic activity, hydrolyzing the linkage between rhamnose and galactose of the O-antigen polysaccharide. Digestion of the LPS brings the capsid near the cell outer membrane (PubMed:20709082, PubMed:4633001).<ref>PMID:16452981</ref> <ref>PMID:20709082</ref> <ref>PMID:4633001</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella phage epsilon15]]
[[Category: Seoane-Blanco M]]
[[Category: Van Raaij MJ]]