View source for 9thk


==Structure of human CLN8 in an apo-state==
<StructureSection load='9thk' size='340' side='right'caption='[[9thk]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9thk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9THK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9THK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9thk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9thk OCA], [https://pdbe.org/9thk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9thk RCSB], [https://www.ebi.ac.uk/pdbsum/9thk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9thk ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CLN8_HUMAN CLN8_HUMAN] Late infantile CLN8 disease;Northern epilepsy. The disease is caused by variants affecting the gene represented in this entry.  The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/CLN8_HUMAN CLN8_HUMAN] Could play a role in cell proliferation during neuronal differentiation and in protection against cell death.<ref>PMID:19431184</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lacabanne D]]
[[Category: Petkevicius K]]
[[Category: Ruprecht JJ]]
[[Category: Sheokand PK]]