View source for 9tux


==PfRIPR bound to monoclonal antibody MAD8-66==
<StructureSection load='9tux' size='340' side='right'caption='[[9tux]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9tux]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9TUX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9TUX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9tux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9tux OCA], [https://pdbe.org/9tux PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9tux RCSB], [https://www.ebi.ac.uk/pdbsum/9tux PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9tux ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RH5IP_PLAF7 RH5IP_PLAF7] Essential for the invasion of host erythrocytes by blood stage merozoites (PubMed:21909261, PubMed:25583518, PubMed:27374406, PubMed:27692771). As part of the PfRH5 adhesion complex, facilitates the interaction of RH5 and human BSG required for the Ca(2+) release into the erythrocyte (PubMed:27374406).<ref>PMID:21909261</ref> <ref>PMID:25583518</ref> <ref>PMID:27374406</ref> <ref>PMID:27692771</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Farrell B]]
[[Category: Higgins MK]]