View source for 9ubx


==The atomic coordinates of the mouse CatSper trimer==
<StructureSection load='9ubx' size='340' side='right'caption='[[9ubx]], [[Resolution|resolution]] 6.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ubx]] is a 30 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UBX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ubx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ubx OCA], [https://pdbe.org/9ubx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ubx RCSB], [https://www.ebi.ac.uk/pdbsum/9ubx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ubx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CTSR2_MOUSE CTSR2_MOUSE] Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization.<ref>PMID:14657366</ref> <ref>PMID:16036917</ref> <ref>PMID:17174296</ref> <ref>PMID:21412339</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Lin S]]
[[Category: Wu J]]
[[Category: Xu Q]]
[[Category: Yan Z]]
[[Category: Zhao Q]]