View source for 9utc


==The VFT domains of human sweet taste receptor TAS1R2 and TAS1R3 in the sucralose-bound state==
<StructureSection load='9utc' size='340' side='right'caption='[[9utc]], [[Resolution|resolution]] 3.33&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9utc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Branchiostoma_lanceolatum Branchiostoma lanceolatum], [https://en.wikipedia.org/wiki/Discosoma_sp. Discosoma sp.] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UTC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.33&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PRD_900090:sucralose'>PRD_900090</scene>, <scene name='pdbligand=RRJ:(2~{S},3~{R},4~{R},5~{R},6~{R})-5-chloranyl-6-(hydroxymethyl)oxane-2,3,4-triol'>RRJ</scene>, <scene name='pdbligand=RRY:1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose'>RRY</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9utc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9utc OCA], [https://pdbe.org/9utc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9utc RCSB], [https://www.ebi.ac.uk/pdbsum/9utc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9utc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TS1R2_HUMAN TS1R2_HUMAN] Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.
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</StructureSection>
[[Category: Branchiostoma lanceolatum]]
[[Category: Discosoma sp]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Hua T]]
[[Category: Liu ZJ]]
[[Category: Shi ZJ]]
[[Category: Wu LJ]]
[[Category: Xu WX]]
[[Category: Yue XL]]