View source for 9uuo


==The NuA3 histone acetyltransferase complex==
<StructureSection load='9uuo' size='340' side='right'caption='[[9uuo]], [[Resolution|resolution]] 3.68&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9uuo]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UUO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.68&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9uuo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9uuo OCA], [https://pdbe.org/9uuo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9uuo RCSB], [https://www.ebi.ac.uk/pdbsum/9uuo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9uuo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/YNG1_YEAST YNG1_YEAST] Histone-binding component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation. YNG1 is required for the HAT activity of NuA3 but not for its integrity. Mediates the interaction of SAS3 with nucleosomes.<ref>PMID:12077334</ref> <ref>PMID:17157260</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Shi WP]]
[[Category: Wang YR]]
[[Category: Zhang HQ]]