View source for 9uuz


==Crystal structure of Thoeris protein ThsA==
<StructureSection load='9uuz' size='340' side='right'caption='[[9uuz]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9uuz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_velezensis Bacillus velezensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UUZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9uuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9uuz OCA], [https://pdbe.org/9uuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9uuz RCSB], [https://www.ebi.ac.uk/pdbsum/9uuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9uuz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THSA_BACAY THSA_BACAY] Probable membrane protein component of the Thoeris antiviral defense system, composed of ThsA and ThsB. Expression of ThsA and ThsB in B.subtilis (strain BEST7003) confers resistance to phages SBSphiC, SBSphiJ and SPO1 (PubMed:29371424). Activation by a signal generated by ThsB leads to phage resistance (By similarity).[UniProtKB:J8G6Z1]<ref>PMID:29371424</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus velezensis]]
[[Category: Large Structures]]
[[Category: Feng Y]]
[[Category: Li D]]
[[Category: Wang H]]