View source for 9vkz


==Cryo-EM structure of retron Ec78 effector protein PtuA hexamer==
<StructureSection load='9vkz' size='340' side='right'caption='[[9vkz]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9vkz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9VKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9VKZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.79&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9vkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9vkz OCA], [https://pdbe.org/9vkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9vkz RCSB], [https://www.ebi.ac.uk/pdbsum/9vkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9vkz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ATP78_ECOLX ATP78_ECOLX] Probable ATPase component of antiviral defense system retron Ec78, composed of a non-coding RNA (ncRNA), a reverse transcriptase (RT), this protein and a putative HNH endonuclease. Expression of retron Ec78 confers protection against bacteriophage T5. At multiplicity of infection (MOI) of 0.02 cultures slow growth when infected with T5 but do not collapse, at MOI 2 cultures enter growth stasis.<ref>PMID:33157039</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Chen L]]
[[Category: Duan L]]
[[Category: Li S]]
[[Category: Qing G]]
[[Category: Zhang K]]