View source for 9vqo


==The structure of DmOR67d-DmOrco in the apo state==
<StructureSection load='9vqo' size='340' side='right'caption='[[9vqo]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9vqo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9VQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9VQO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9vqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9vqo OCA], [https://pdbe.org/9vqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9vqo RCSB], [https://www.ebi.ac.uk/pdbsum/9vqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9vqo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OR67D_DROME OR67D_DROME] Odorant receptor for the fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA). Acts in concert with Snmp and lush to capture cVA molecules on the surface of Or67d expressing olfactory dendrites and facilitate their transfer to the odorant-receptor Orco complex. Necessary to mediate behavioral responses to cVA by regulating both male and female mating behavior. Activation of Or67d neurons by cVA inhibits courtship of other males, whereas in females their activation promotes receptivity to other males.<ref>PMID:16928861</ref> <ref>PMID:17363250</ref> <ref>PMID:17392786</ref> <ref>PMID:17943085</ref> <ref>PMID:18305480</ref> <ref>PMID:19966787</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Guo J]]
[[Category: Wang J]]